|Runner-Up||Wake Forest (1st CWS Appearance)|
|Winning coach||Bibb Falk(1st title)|
The 1949 NCAA Baseball Tournament was the third NCAA-sanctioned baseball tournament that determined a national champion. The tournament was held as the conclusion of the 1949 NCAA baseball season. The College World Series was played at Wichita Municipal Stadium in Wichita, Kansas from June 22 to June 25. The third tournament's champion was the Texas Longhorns, coached by Bibb Falk. The Most Outstanding Player was named for the first time, with the inaugural award going to Tom Hamilton of Texas. This was the first of six championships for the Longhorns through the 2012 season.
The tournament was divided into four regional brackets, Region A, Region B, Region C and Region D, with each region consisting of two teams playing a best-of-three game series. The winner of each bracket advanced to the College World Series. This was the first and only year of this format.
As in previous years, each representative of the eight districts were determined by a mix of selection committees, conference champions, and district playoffs.
|School||Conference||Record (Conference)||Berth||Previous NCAA Appearances|
|Boston College||District I Selection||None|
|Colorado State[a]||District VII Selection||1|
|Notre Dame||Won District IV Playoff||None|
|Oklahoma A&M||MVC||Won District V Playoff||1|
|Southern California||CIBA||34-11-1 (12-2)||District VIII Selection (Won PCC)||1|
|St. John's||19-4||Won District II Playoff||None|
|Texas||SWC||18-7 (12-3)||District VI Selection (Won SWC)||1|
|Wake Forest||Southern||27-2 (13-1)||Won District III Playoff||None|
Following financial losses in Kalamazoo, Michigan the previous year, the NCAA moved the tournament to Wichita for the 1949 edition. This would be the only year in Wichita, as the 1950 edition would take place in Omaha, Nebraska, as it has every year through 2012.
|School||Conference||Record (Conference)||Head Coach||CWS Appearances||CWS Best Finish||CWS Record|
|St. John's||21–4 (n/a)||Frank McGuire||0
|Southern California||CIBA||36–12–1 (12–2)||Sam Barry||1
|Texas||SWC||20–7 (12–3)||Bibb Falk||0
|Wake Forest||Southern||29–2 (13–1)||Taylor Sanford||0
|June 22||Game 1||Wake Forest||2–1||Southern California|
|Game 2||Texas||7–1||St. John's|
|June 23||Game 3||Texas||8–1||Wake Forest|
|Game 4||Southern California||12–4||St. John's||St. John's eliminated|
|June 24||Game 5||Wake Forest||2–112||Southern California||Southern California eliminated|
|June 25||Final||Texas||10–3||Wake Forest||Texas wins CWS|