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CAS Number
PubChem CID
Chemical and physical data
Molar mass421.410 g/mol
3D model (JSmol)

AM-087 (part of the AM cannabinoid series) is an analgesic drug which acts as a cannabinoid agonist.[1] It is a derivative of ?8THC substituted on the 3-position side chain. AM-087 is a potent CB1 agonist with a Ki of 0.43nM, making it around 100x more potent than THC itself. This is most likely due to the bulky bromine substituent on the side chain.[2]

See also


  1. ^ Martin, Billy R.; Compton, David R.; Semus, Simon F.; Lin, Sonyuan; Marciniak, Gilbert; Grzybowska, Jolanta; Charalambous, Avgui; Makriyannis, Alexandros (1993). "Pharmacological evaluation of iodo and nitro analogs of ?8-THC and ?9-THC". Pharmacology Biochemistry and Behavior. 46 (2): 295-301. doi:10.1016/0091-3057(93)90356-X. ISSN 0091-3057.
  2. ^ Charalambous A, et al. Pharmacological evaluation of halogenated delta 8-THC analogs. Pharmacology Biochemistry and Behavior. 1991 Nov;40(3):509-12. PMID 1666915

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