Charles Frederick DeShane (December 10, 1918 - November 5, 2006) was a professional American football player in the National Football League for the Detroit Lions from 1945 to 1949.
Born in Waukesha, Wisconsin, DeShane was the starting quarterback for the University of Alabama in 1939 and 1940 and was named to the All-Southeastern Conference team his senior season. He coached football from 1942 to 1944 at his alma mater, Creston High School (Grand Rapids, Michigan), before signing with the Lions.
From 1945 to 1946, Deshane played quarterback and linebacker for the Lions. He played guard from 1947 to 1949.
DeShane was also a railroad conductor during the offseasons. He was married to his wife Evelyn for 31 years and had four children, 14 grandchildren and 21 great-grandchildren. He died in Grand Rapids, Michigan.