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Frankenstein is often considered the classic exposition of this theme, with a scientifically created human becoming a destructive monster.
It is also a common theme in science fiction, with Blade Runner, The Terminator and The Matrix being popular examples. Another example would be in "2001: A Space Odyssey" when Frank and Dave battle their flight computer, the HAL 9000.
Conflict (narrative) for a list of narrative conflicts.
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