Postarthroscopic Glenohumeral Chondrolysis
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Postarthroscopic Glenohumeral Chondrolysis
Postarthroscopic glenohumeral chondrolysis
Blausen 0797 ShoulderJoint.png
Human shoulder(joint)
Risk factorscomplication of arthroscopic surgery

Postarthroscopic glenohumeral chondrolysis (PAGCL) is a rare complication of arthroscopic surgery and involves chondrolysis wherein the articular cartilage of the shoulder undergoes rapid, degenerative changes shortly after arthroscopic surgery.[1]


Bupivacaine, lidocaine, ropivacaine and levobupivacaine are all toxic to cartilage and their intra-articular infusions can lead to this toxic effect.[2] Intra-articular pain pumps with local anesthetics have been implicated as a potential cause.[3]



Total Joint Arthroplasty or reverse total joint arthroplasty (shoulder replacement surgery)


  1. ^ Yeh, PC; Kharrazi, FD (February 2012). "Postarthroscopic glenohumeral chondrolysis". The Journal of the American Academy of Orthopaedic Surgeons. 20 (2): 102-12. doi:10.5435/JAAOS-20-02-102. PMID 22302448.
  2. ^ Gulihar, Abhinav; Robati, Shibby; Twaij, Haider; Salih, Alan; Taylor, Grahame J.S. (December 2015). "Articular cartilage and local anaesthetic: A systematic review of the current literature". Journal of Orthopaedics. 12: S200-S210. doi:10.1016/j.jor.2015.10.005. PMC 4796530. PMID 27047224.
  3. ^ Busfield, Benjamin T.; Romero, Denise M.; Korshad, Daniel; Kharrazi, F. Daniel (June 2014). "Subacromial pain pump use is safe after arthroscopic rotator cuff repair". Journal of Orthopaedics. 11 (2): 64-67. doi:10.1016/j.jor.2014.04.012. PMC 4118566. PMID 25104887.

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