The historical application of Biotechnology throughout is provided below in order. These discoveries, inventions and modifications are evidence of the evolution of biotechnology since before the common era.
^C A Hutchison, 3rd, S Phillips, M H Edgell, S Gillam, P Jahnke and M Smith (1978). "Mutagenesis at a specific position in a DNA sequence". J Biol Chem. 253: 6551-6560. PMID681366.CS1 maint: Multiple names: authors list (link)