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|Headquarters||Irvine, CA (headquarters)|
|Larry Jia (Chairman and CEO)|
Zymo Research is a privately-held American manufacturer of molecular biology research tools used for DNA and RNA research and analysis. The company also supports epigenetics research, the field of medicine studying stable heritable traits that cannot be explained by changes in DNA sequence.
Zymo Research Corporation was founded by Larry Jia in 1994. The company started its home base in Orange, CA in a garage, manufacturing products for DNA and RNA extraction and purification and other specialty products for E. coli and yeast based research. It expanded its product offerings to include tools for epigenetics research. In December 2010, the company relocated to Irvine, CA.
In 2009, Zymo Research Europe was established in Freiburg, Germany. It works as a distribution support hub for Europe and the Middle East and will also be initiating research and development programs at a new facility, intended for state-of-the-art researching.[when?]
The company is a supplier of DNA extraction and RNA extraction kit products used to isolate and purify DNA and RNA from various sample sources ranging from tough to lyse environmental samples to tissue, blood, and serum samples. The company expanded and by 2017 was also an epigenetics company, offering products in DNA methylation and DNA hydroxymethylation.
Zymo Research develops epigenetics products for CpG methylation detection and quantitation. Many of these products exploit the bisulfite conversion approach, wherein unmethylated cytosine is converted to uracil, allowing for downstream sequencing analysis. The company also offers polymerases optimized for polymerase chain reaction (PCR) analysis of bisulfite-converted DNA, as well as antibodies for IP-based epigenetics research.
In addition to their methylation portfolio, Zymo Research offers product lines for analysis of 5-hydroxymethylcytosine. In late 2010, the company became the first to offer a kit for locus specific 5-hydroxymethylcytosine detection (protection, digestion, amplification).
The company's products are distributed in North America and internationally through distributors located in Europe, Asia, South America, Africa, Australia, and others.